Manufacturer of N-terminal pro brain natriuretic peptide (NT proBNP) detection kit Shanghai Kaichuang biology

BNP is the protease cleavage product of brain natriuretic peptide precursor (preprobnp)
Preprobnp is synthesized in cardiomyocytes, and the signal peptide is removed to become pro brain natriuretic peptide (proBNP) molecule
After being stimulated by cardiomyocytes (such as cardiomyocyte stretching), proBNP is cleaved into two polypeptides under the action of protease, namely inactive NT proBNP and bioactive enzyme BNP
Both polypeptides are secreted into the blood and circulated in the blood
NT proBNP is secreted by the ventricle and has a straight chain structure
It has no biological activity and is cleared by the kidney; The half-life was 90-120 min and stable in vitro; The blood concentration was high (5-20 times bnp15), and the blood concentration was positively correlated with the degree of cardiac dysfunction; NT proBNP level is not affected by body position, daily activities and other factors, nor does it fluctuate within or between days, so it has good repeatability
　　NT-proBNP—& mdash; Sensitive and specific markers of cardiac function Product Description: the N-terminal pro brain natriuretic peptide (NT proBNP) detection kit (colloidal gold method) is specially used by medical institutions in conjunction with the immunochromatographic quantitative analyzer produced by Shanghai Kaichuang Biotechnology Co
, Ltd
It adopts colloidal gold immunochromatographic technology and double antibody sandwich method to quantitatively determine the concentration of N-terminal pro brain natriuretic peptide (NT proBNP) in human serum, plasma and whole blood in vitro
It is used for early clinical detection of heart failure patients, risk stratification of heart failure patients, monitoring heart failure treatment and drug efficacy evaluation, judging the prognosis of heart failure patients, and making rapid auxiliary diagnosis Product advantages: quantitative detection, one-step detection of sensitive and specific markers of cardiac function, ultra wide detection range of 100 ~ 25000 pg / ml in 15 minutes, high specificity, no interference of bilirubin, cholesterol and hemoglobin, no buffer treatment of samples, simple and convenient operation, N-terminal pro brain natriuretic peptide (NT proBNP) detection kit product www
biochemtron
com com/product/znfx1/2018-09-08/27
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: hxzzz 20172400391