Yunnan polosham 407 factory sales

Lom Yunnan Guizhou Sichuan Guangxi Gansu Hunan Guangdong Kunming Qujing Yuxi Zhaotong Baoshan Lijiang Pu'er Lincang Dehong Nujiang Diqing Shangri La Dali Chuxiong Honghe Wenshan Xishuangbanna where there is poloxamer 407 cheap manufacturer agent wholesaler level: how much is the price of pharmaceutical excipient poloxamer 407 CAS: 9003-11-6 Standard: Enterprise Standard Molecular formula: Ho (C2H4O) a (C3H6O) B (C2H4O) ah molecular weight: 9840 ~ 14600 content: molecular weight: 9840 ~ 14600 appearance: white powder Packaging: 90kg / cardboard barrel Extended products: solid grade Uses: 1
As emulsifier and stabilizer: poloxamer188 (Pluronic F68), as an oil in water emulsifier, is one of the few synthetic emulsifiers used in intravenous emulsion at present
The dosage is 0
1% ~ 5%
The emulsion prepared with this product has few emulsion particles, generally within 1-MU; Below m, the absorption rate is high
It has stable physical properties and can withstand hot pressure sterilization and low temperature freezing
2 as a solubilizer: This product can form micelles due to surfactants to increase the surface solubility of various drugs
3 as an absorption promoter: on the one hand, this product slows the intestinal peristalsis, increases the residence time of drugs in the gastrointestinal tract and increases the absorption, which can improve the bioavailability of oral preparations
On the other hand, this product has good compatibility with the skin, increases the skin permeability and promotes the absorption of topical drugs
4 as a slow release material: solid products with large molecular weight, used as adhesives, coating materials, etc
to prepare tablets, capsules, gels, etc
, to achieve sustained release and controlled release purposes, and achieved satisfactory results
The dosage is 5% ~ 15%
5 as solid dispersant: solid products can be used as carriers of solid dispersions, such as butazone, griseofulvin, digitalis and the solid dispersions prepared by this product, which greatly improves the solubility of these drugs and promotes the absorption of these drugs
The dosage is 2% ~ 10%
6 this product, which is used as the solid model of cream and suppository matrix, is not only soluble, but also can promote the absorption of drugs
It can also play a slow-release role when used as the matrix